Analysis Of Ribosomal Dynamics As Revealed By Cryo-EM And Flexible Fitting
نویسندگان
چکیده
منابع مشابه
Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM
Helix 38 (H38) of the large ribosomal subunit, with a length of 110 A, reaches the small subunit through intersubunit bridge B1a. Previous cryo-EM studies revealed that the tip of H38 moves by more than 10 A from the non-ratcheted to the ratcheted state of the ribosome while mutational studies implicated a key role of flexible H38 in attenuation of translocation and in dynamical signaling betwe...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2009
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2008.12.3037